Mary Rheuben, PhD
Professor
B-142 Life Sciences
East Lansing MI 48823-1317
Phone: (517) 353-4754
E-mail: rheuben@msu.edu
Education and Training:
PhD, Neurobiology, University of California-San Diego, 1971
BA, Zoology, University of California-Davis, 1966
Research Interests:
- Development and function of neuromuscular synapses using normal and mutant Drosophila to analyze these processes at the cellular and molecular levels
- Mathematical modelling of muscle fibers and dendrites receiving multiple synchronous synaptic inputs
Recent Publications:
Tai MH, Rheuben MB, Autio DM, and Zipser B. Leech photoreceptors project their galectin-containing processes into the optic neuropile where they contact AP cells. J. Comp. Neurol. 371:235-248, 1996.
Rheuben MB, Autio DM, Yao AZ, and Atchison WD. Effects of the paralytic agent 2,4-dithiobiuret on viability and morphology of rat pheochromocytoma (PC12) cells. Neurotoxicology. 18:105-122, 1997.
Yoshihara M, Rheuben MB, and Kidokoro Y. Transition from growth cone to functional motor nerve terminal in Drosophila embryos. J. Neuroscience. 17:8408-8426, 1997.
Rheuben MB, Autio DM, and Atchison WD. Endocytic recycling of vesicular structures in 2-4, dithiobiuret (DTB) treated motor nerve terminals. Soc. Neurosci. Abstr. Vol 24, Part 1:78, 1998.
Rheuben MB, Yoshihara M, and Kidokoro Y. Ultrastructural correlates of neuromuscular junction development. In: Neuromuscular Junctions in Drosophila, International Review of Neurobiology. 43:69-92, 1999. Vivian Budnik and L. Sian Gramates, Eds. Academic Press.
Takasu-Ishikawa E, Yoshihara M., Ueda A, Rheuben MB, Hotta Y, and Kidokoro Y. Screening for synaptic defects revealed a locus involved in presynaptic and postsynaptic functions in Drosophila embryos. J. Neurobiol. 48:101-119, 1999.
Rheuben MB, Yoshihara M, Kuromi H, and Kidokoro Y. Ultrastructural analysis of endocytosis in Drosophila larvae. Soc. Neurosci. Abstr. Vol. 27. 2001.
Xu YF, Autio DM, Rheuben MB, and Atchison WD. Impairment of synaptic vesicle trafficking at motor nerve terminals of mice treated with 2,4-dithiobiuret. J. Neurophysiol. 88:3243-3258, 2002.
Rheuben MB, Autio DM, Xu YF, and Atchison WD. Morphometric characterization of the neuromuscular junction of rodents intoxicated with 2,4-dithiobiuret: evidence that nerve terminal recycling processes contribute to muscle weakness. Toxicology and Applied Pharmacology. 196:266-286, 2004.
Verzi DW, Rheuben MB, and Baer SM. Impact of time-dependent changes in spine density and spine shape on the input-output properties of a dendritic branch: A computational study. J. Neurophysiol. 93:2073-2089, 2005.
